Winter 1986.
Methods | Multicentre, randomised trial. | |
Participants | 100 people with ST. Not reported if participants were hospitalised or non‐hospitalised or if the diagnosis of ST was objectively confirmed by ultrasonography. | |
Interventions | Diclofenac emulgel. Heparin gel. Study treatment given 14 days. |
|
Outcomes | Pain (spontaneous and after pressure), redness, palpable cord. | |
Notes | Study only reported as an abstract for a scientific meeting. No full paper available. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Randomisation list. |
Allocation concealment (selection bias) | Unclear risk | Method of allocation concealment not reported. |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | No information on study medication or outcome assessment provided. |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Authors did not report whether they performed an ITT analysis. |
Selective reporting (reporting bias) | Unclear risk | Outcomes not specified, only a general outcome of "efficacy" reported. |
bid: twice daily; COI: conflicts of interest; COX: cyclo‐oxygenase; CUS: compression ultrasound; DVT: deep vein thrombosis; ECB: elastic compression bandage; HIT: heparin‐induced thrombocytopenia; im: intramuscularly; ITT: intention to treat; IU: international units; LMWH: low molecular weight heparin; NSAID: non‐steroidal anti‐inflammatory drug; od: once daily; PE: pulmonary embolism; RCT: randomised controlled trial; sc: subcutaneously; SD: standard deviation; SF‐36: 36‐item Short Form; ST: superficial thrombophlebitis; tid: three times daily; UFH: unfractionated heparin; VAS: visual analogue scale;‐ VRAS: visual rating analogue scale; VRS: visual rating scale.