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. Author manuscript; available in PMC: 2020 Jan 10.
Published in final edited form as: Matrix Biol. 2015 Dec 12;49:61–81. doi: 10.1016/j.matbio.2015.12.005

Fig. 5.

Fig. 5.

Biglycan-dependent translocation of p47phox is mediated by MyD88. (A) Confocal images of F4/80 (green) and p47phox (red) in macrophages isolated from WT and Trif−/− mice upon 2 h pre-incubation with MyD88 inhibitor (50 μM) or the scrambled MyD88 inhibitor control, and treatment with biglycan for 40 min (4 μg/ml). Inserts in the confocal images represent line-scanned profiles, while the white arrows indicate the distance within which the scans were generated. Bar = 10 μm. (B) Quantification of p47phox co-localization with F4/80 from (A) given as dot plot for the mean correlation index (Icorr) ± S.D. of at least 10 cells per condition; *P < 0.05.