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. Author manuscript; available in PMC: 2020 Dec 4.
Published in final edited form as: Exp Neurol. 2019 Dec 5;325:113142. doi: 10.1016/j.expneurol.2019.113142

Figure 4. Key role of Nrf2 in PC-mediated neuroprotection in vitro.

Figure 4.

Primary mouse neurons from Nrf2 KO mice were subjected to PC (12-min OGD) and lethal OGD (1-h OGD). (A) Live/Dead cell staining, (B) dead neuron counting, (C) MTT assay, and (D) LDH release assay demonstrate that PC fails to elicit neuroprotection in Nrf2 KO neurons. n=3–6, *** p≤0.001 vs Ctrl; n.s.: not significant. Scale bar: 10 μm.