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. 2019 Dec 6;2019(12):CD003907. doi: 10.1002/14651858.CD003907.pub5

Comparison 5. Aerobic exercise versus no training in facioscapulohumeral muscular dystrophy.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Maximum voluntary isometric knee extension strength 1 19 Mean Difference (IV, Fixed, 95% CI) ‐47.30 [‐108.02, 13.42]
2 Maximum voluntary isometric knee extension strength 1 52 Mean Difference (IV, Fixed, 95% CI) 0.10 [‐0.66, 0.86]
3 Maximum voluntary isometric knee flexion strength (N) 1 19 Mean Difference (IV, Fixed, 95% CI) ‐7.5 [‐55.63, 40.63]
4 Maximum voluntary isometric elbow flexion strength (N) 1 19 Mean Difference (IV, Fixed, 95% CI) 5.8 [‐15.27, 26.87]
5 Maximum voluntary isometric elbow extension strength (N) 1 19 Mean Difference (IV, Fixed, 95% CI) 0.5 [‐19.25, 20.25]
6 Muscle strength leg (N) 1 12 Mean Difference (IV, Fixed, 95% CI) 8.0 [‐16.19, 32.19]
7 Muscle strength arm (N) 1 12 Mean Difference (IV, Fixed, 95% CI) 16.0 [‐3.29, 35.29]
8 Maximal workload (W) 1 19 Mean Difference (IV, Fixed, 95% CI) 21.5 [2.19, 40.81]
9 Maximal workload (W) 1 12 Mean Difference (IV, Fixed, 95% CI) 18.8 [13.67, 23.93]
10 VO2 peak (mL/min/kg) 1 19 Mean Difference (IV, Fixed, 95% CI) 3.60 [0.63, 6.57]
11 VO2 peak (mL/min/kg) 1 12 Mean Difference (IV, Fixed, 95% CI) 3.30 [2.51, 4.09]
12 VO2 peak (L/min) 1 38 Mean Difference (IV, Fixed, 95% CI) 1.1 [0.43, 1.77]
13 Distance walked in 6‐min walk test (m) 1 19 Mean Difference (IV, Fixed, 95% CI) 28.9 [4.21, 53.59]
14 Distance walked in 6‐min walk test (m) 1 52 Mean Difference (IV, Fixed, 95% CI) 31.00 [19.34, 42.66]
15 Distance walked in 6‐min walk test (m) 1 12 Mean Difference (IV, Fixed, 95% CI) 7.90 [‐18.37, 34.17]
16 5‐times sit to stand (s) 1 12 Mean Difference (IV, Fixed, 95% CI) ‐0.03 [‐7.61, 7.55]
17 Quality of life ‐ Sickness Impact Profile (0‐572) 1 52 Mean Difference (IV, Fixed, 95% CI) ‐10.0 [‐19.64, ‐0.36]
18 Pain ‐ visual analogue scale (0‐10) 1 52 Mean Difference (IV, Fixed, 95% CI) ‐1.0 [‐1.00, 1.00]
19 Fatigue 1 19 Mean Difference (IV, Fixed, 95% CI) ‐1.2 [‐2.96, 0.56]
20 Fatigue 1 52 Mean Difference (IV, Fixed, 95% CI) ‐7.3 [‐8.14, ‐6.46]