Table 1.2.
Classification of patients with acute graft-versus-host disease
| Clinical staging | ||||
|---|---|---|---|---|
| Stage | Skin | Liver | Gut | |
| + | Rash < 25% | BSA Total bilirubin 2–3 mg/dL | Diarrhea 500–1000 mL/day | |
| + + | Rash 25–50% BSA | Total bilirubin 3–6 mg/dL | Diarrhea 1000–1500 mL/day | |
| + + + | Generalized erythroderma | Total bilirubin 6–15 mg/dL | Diarrhea > 1500 mL/day | |
| + + + + | Desquamation and bullae | Total bilirubin > 15 mg/dL | Pain, with or without ileus | |
| Clinical grading | ||||
| Stage |
||||
| Grade | Skin | Liver | Gut | PS |
| 0 (none) | 0 | 0 | 0 | 0 |
| I | + to + + | 0 | 0 | 0 |
| II | + to + + + | + | + | + |
| III | + + to + + + | + + to + + + | + + to + + + | + + |
| IV | + + to + + + + | + + to + + + + | + + to + + + + | + + + |
BSA = body surface area, PS = performance status