Figure 1.

Diagnoses of the 262 patients enrolled in pediatric phase I trials at the National Cancer Institute. The diagnoses were: brain tumor (n = 92); Ewing’s sarcoma (n = 35); other sarcoma (n = 33), which includes alveolar soft part sarcoma, desmoplastic round cell tumor, synovial sarcoma, and undifferentiated sarcoma; osteosarcoma (n = 26); rhabdomyosarcoma (n = 17); neuroblastoma (n = 27); Wilms’ tumor (n = 6); and other (n = 26), which includes carcinoma (n = 15), lymphoma (n = 1), germ-cell tumor (n = 2), and other embryonal tumors (n = 8), such as hepatoblastoma, pancreatoblastoma, and pleuropulmonary blastoma.