Table 5.

Results of analyses focusing on chronic/treatment‐resistant and mild/moderate/severe depression (all with response as outcome)

	Pairwise meta‐analyses						Network meta‐analyses
	N	RR	95% CI	I2	95% CI	Egger	RR	95% CI	χ2 (df), p
Chronic or treatment‐resistant depression
Combined vs. psychotherapy	3	1.45	1.16‐1.79	55	0‐86	1.00	1.59	1.23‐2.04	2.47 (2), 0.29
Combined vs. pharmacotherapy	10	1.41	1.12‐1.75	73	41‐84	0.37	1.39	1.15‐1.67
Psychotherapy vs. pharmacotherapy	6	0.84	0.70‐1.00	25	0‐70	0.37	0.87	0.68‐1.10
Severe depression
Combined vs. psychotherapy	2	1.35	0.85‐2.17	65	NA	NA	1.33	0.91‐1.92	0.66 (3), 0.88
Combined vs. pharmacotherapy	6	1.45	1.14‐1.82	35	0‐73	0.80	1.45	1.10‐1.89
Psychotherapy vs. pharmacotherapy	4	1.18	0.70‐1.96	54	0‐83	0.33	1.09	0.72‐1.64
Moderate depression
Combined vs. psychotherapy	11	1.14	0.99‐1.30	0	0‐51	0.30	1.19	1.05‐1.37	0.48(30), 0.92
Combined vs. pharmacotherapy	18	1.28	1.10‐1.47	34	0‐62	0.03	1.23	1.09‐1.41
Psychotherapy vs. pharmacotherapy	32	1.02	0.93‐1.12	23	0‐50	0.35	1.03	0.94‐1.14
Mild depression
Combined vs. psychotherapy	1	1.39	0.65‐2.94	0	NA	NA	0.97	0.52‐1.82	0.89(1), 0.35
Combined vs. pharmacotherapy	1	0.85	0.56‐1.30	0	NA	NA	1.04	0.57‐1.89
Psychotherapy vs. pharmacotherapy	5	1.14	0.77‐1.69	52	0‐81	0.79	1.08	0.75‐1.54

RR – relative risk, NA – not available

Significant results are highlighted in bold prints