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. 2020 Jan 7;12:100242. doi: 10.1016/j.bonr.2020.100242

Fig. 3.

Fig. 3

NSG oc/oc mice present osteoclast-rich osteopetrosis. a Calcium and phosphorus serum levels in NSG and NSG oc/oc mice (n ≥ 8 per genotype). **p < 0.01, ****p < 0.0001. b Representative images of decalcified formalin-fixed paraffin-embedded vertebral sections of NSG and NSG oc/oc mice stained with H/E (upper panels) and TRAP (middle panels); undecalcified formalin-fixed resin-embedded vertebral sections stained with von Kossa/van Gieson staining (lower panels). Scale bar: 500 μm. c In vitro osteoclastogenesis from splenic precursors of NSG and NSG oc/oc mice: representative images of TRAP staining on plastic (upper panels) and of Toluidine blue staining of resorption pits on dentin discs (lower panels). Scale bars: 400 μm.