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. 2020 Jan 7;12:100242. doi: 10.1016/j.bonr.2020.100242

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© 2020 Published by Elsevier Inc.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Supplementary Fig 2 — Immunophenotypic analysis of splenocytes from NSG oc/oc and control mice. a Representative FACS analysis of splenocytes from C57BL/6J adult WT mice, serving as technical control (top panels), from NSG mice (middle panels) and from NSG oc/oc mice (bottom panels), after red blood cells lysis. Erythroid cells are defined as TER119⁺NKp46^-CD11b^-B220^-CD4^-CD8^- (highlighted in red); NK cells as TER119^-NKp46⁺CD11b^-B220^-CD4^-CD8^- (light blue); myeloid cells as TER119^-NKp46^-CD11b⁺B220^-CD4^-CD8^- (green); B cells as TER119^-NKp46^-CD11b^-B220⁺CD4^-CD8^- (orange); CD4 and CD8 T lymphocytes as TER119^-NKp46^-CD11b^-B220^-, CD4⁺CD8^- or CD4^-CD8⁺, respectively (dark blue). b Histogram showing mean percentage of splenic subpopulations depicted in a in the spleen of NSG and NSG-oc/oc mice. *p < 0.05; **p < 0.01.