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. Author manuscript; available in PMC: 2020 Jan 10.
Published in final edited form as: Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 Apr 21;3(7):591–598. doi: 10.1016/j.bpsc.2018.03.018

Figure 1.

Figure 1.

Alcohol-induced change in ventral striatal D2/3 receptor binding (ventral striatum [VST] percent change in binding potential [ΔBPND], the percent decrease from placebo day to alcohol day) by group and drink order. The family history–positive (FHP) group showed an opposite response to the drink conditions compared with the family history–negative (FHN) and alcohol use disorder (AUD) groups (p = .02, group-by-order interaction). Plot symbols indicate group mean and error bars indicate SEM. Participant group sizes were FHP: n = 8 alcohol beverage at first scan (AP) and n = 8 alcohol beverage at second scan (PA); FHN: n = 15 AP and n = 17 PA; AUD: n = 8 AP and n = 7 PA (data shown in Supplemental Table S3).