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. Author manuscript; available in PMC: 2020 Dec 12.
Published in final edited form as: Exp Gerontol. 2019 Dec 13;131:110767. doi: 10.1016/j.exger.2019.110767

Figure 4: Aged NRF2KO mice have cognitive deficits relative to aged WT animals.

Figure 4:

(A) In both phases of the ODRL 20 month old NRF2KO mice took more trials to reach criterion than age-matched WT mice. There was no difference due to genotype in either phase in the number of trials to reach criteria for the 6 month old mice (B) Aged NRF2KO mice froze significantly less in the CFR test than aged matched WT mice. There were no differences in freezing times between genotypes in the 6 month old animals. n=5–8 animals per condition,*p<0.05, **p<0.01