Skip to main content
. Author manuscript; available in PMC: 2020 Dec 12.
Published in final edited form as: Exp Gerontol. 2019 Dec 13;131:110767. doi: 10.1016/j.exger.2019.110767

Figure 5: Aged NRF2KO animals have reduced hippocampal and cortical expression of synaptic and mitochondrial genes.

Figure 5:

The expression of synaptic genes reduced in the (A) hippocampus and (B) frontal cortex on aged NRF2KO mice as compared to age matched WT mice but no changes were observed in young animals. A trend toward reduced expression of ETC genes was likewise observed in the (C) hippocampus and (D) frontal cortex of aged NRF2KO mice relative to their age matched controls but again no effect was seen in young animals. All gene expression shown is fold induction relative to the WT animals of that age and gender. n=5–8 mice of each gender per genotype, *p<0.05.