Skip to main content
. 2019 Oct 15;28(1):42–51. doi: 10.1016/j.ymthe.2019.10.007

Figure 2.

Figure 2

[18F]-TMP Uptake in eDHFR Cells In Vitro and In Vivo

(A) Time course of in vitro uptake of [18F]-TMP in eDHFR-transduced HCT116 cells with MTX (10 μM) and unlabeled TMP (10 μM) as blocking agents (n = 4). (B) Similar to (A) but with NTD, control HCT116 cells. (C) Scheme of location of eDHFR HCT116 and control tumors. (D) Representative small animal PET/CT images in axial and coronal planes. (E) Time course quantification of eDHFR tumor uptake compared to control from (D) (n = 3). Error bars represent the SD.