Fig. 3.

Interaction analysis between microstructural damage and basic executive performance. The figure shows white-matter patterns indicating a performance-by-group interaction effect between basic executive performance (i.e., C3) and microstructural indices (MD: light blue, AD: yellow) in AUD patients vs. healthy controls, within damaged tracts observed in AUD patients. In particular, we observed a significant (negative) relationship between basic executive performance (i.e., C3) and MD/AD indices in AUD patients (MD: r = −0.59, p = 0.004; AD: r = −0.45, p = 0.02), but not in healthy controls (MD: r = −0.04, p = 0.872; AD: r = 0.24, p = 0.338).