Figure 5.
Cellular uptake of FAM-siRNA complexes under hypoxia conditions at 4 hr (A) and the representative FAM-siRNA complexes at different time points (1, 2, and 4 hr) (B) in MP-38 cells determined using flow cytometry. The relative mean fluorescence (MFI) is the fold change compared to the no complexes or siRNA treated group. A commercial agent DharmaFECT 1 (DF) was studied as a control. Statistical analysis comparing the developed complexes to the DF group at the same time point. * p<0.05; *** p<0.001.