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. Author manuscript; available in PMC: 2021 Jan 5.

Published in final edited form as: Int J Pharm. 2019 Nov 23;573:118894. doi: 10.1016/j.ijpharm.2019.118894

Figure 6. — Cellular uptake of Chi/FAM-siRNA (N/P ratio: 40/1) (A) and HA-coated Chi/FAM-siRNA (C/N/P ratio: 40/40/1) (B) complexes (magnification: 100X) in MP-38 cells under hypoxia conditions at different duration (1, 2, and 4 hr). (C) Z-stack images of cellular uptake of Chi/FAM-siRNA (N/P: 40/1) and HA-coated Chi/FAM-siRNA (C/N/P: 40/40/1) in MP-38 cells under hypoxia conditions at 2 hr and 4 hr, respectively. Images were taken by CLMS. Green signal: FAM; Blue signal: Hoechst; Red signal: LysoTracker™.

Figure 6. — Cellular uptake of Chi/FAM-siRNA (N/P ratio: 40/1) (A) and HA-coated Chi/FAM-siRNA (C/N/P ratio: 40/40/1) (B) complexes (magnification: 100X) in MP-38 cells under hypoxia conditions at different duration (1, 2, and 4 hr). (C) Z-stack images of cellular uptake of Chi/FAM-siRNA (N/P: 40/1) and HA-coated Chi/FAM-siRNA (C/N/P: 40/40/1) in MP-38 cells under hypoxia conditions at 2 hr and 4 hr, respectively. Images were taken by CLMS. Green signal: FAM; Blue signal: Hoechst; Red signal: LysoTracker™.