Table 3.

Summary of key model input parameters and distribution for the sensitivity analyses

Item	Mean	SE	Distribution for PSA	Source
Utilities
Complete protectionb	0.9	0.18	Beta	Cawston 2017 [20]
Complete responsec	0.7	0.14	Beta	Cawston 2017 [20]
Incomplete responsed	0.24	0.048	Beta	Cawston 2017 [20]
HCRU costa
Cost per patient with severe nauseae	$9920	$820	Gamma	Burke 2011 [5]

HCRU, healthcare resource use; PSA, probabilistic sensitivity analysis; SE, standard error

^aAdjusted to 2018 US dollars

^bComplete protection (CP) defined as absence of any of an emetic episode or use of rescue medication and no significant nausea (visual analogue scale [VAS] score < 25 mm)

^cComplete response (CR) defined as no emetic episodes or rescue medication with a VAS score ≥ 25 mm

^dIncomplete response (IR) if there was no CP or CR

^eSevere nausea defined as VAS > 80 mm