Table 2.
Expression of TLR-4, ROS, VDR, CYP27, CYP24, IL-6, TNF-α, IL-10, cathelicidin, MCP-1 and NF- κB.
| Healthy pool (HS) | Uremic pool (US) | |||
|---|---|---|---|---|
| HS | HS + 25 vitamin D | US | US + 25 vitamin D | |
| Expression (MIF) | ||||
| TLR4 |
716 (654–936) |
644 (644–870) |
2653* (1853–3372) |
1692† (1022–2292) |
| ROS |
343 (313–498) |
378 (320–563) |
550* (394–607) |
544 (435–599) |
| VDR |
7882 (6574–9687) |
8394 (6475–10708) |
7657 (6670–9420) |
7556 (5699–9420) |
| CYP27 |
1201 (692–1461) |
1207 (747–1521) |
1396 (931–1532) |
1170 (955–1521) |
| CYP24 |
439 (319–563) |
363 (329–501) |
342 (331–676) |
375 (333–485) |
| Cytokines (pg/mL) | ||||
| IL-6 |
3.8 (3.3–4.9) |
3.6 (3.1–5.3) |
39.3* (28.3–45.3) |
37.3 (28.8–42.5) |
| TNF-α |
2.2 (1.6–2.7) |
2.3 (2.1–3.2) |
3.9* (3.2–4.7) |
3.4 (2.9–4.8) |
| IL-10 |
45 (41–62) |
47 (45–62) |
61* (53–64) |
60 (56–73) |
| CATHELICIDIN |
0.44 (0.43–0.46) |
0.43 (0.4–0.49) |
0.58* (0.51–0.65) |
0.52† (0.48–0.59) |
| MCP-1 |
11076 (7899–11948) |
7336 (4820–8905) |
14370* (9117–16936) |
7697† (5940–10310) |
| NF- κB (%) |
4.8 (1.6–1.2) |
3.1 (1.7–3.4) |
3.4 (2.1–5.5) |
4.1 (2.3–6.4) |
*US ≠ HS: p < 0.04.
†US + 25 vitamin D ≠ US: p < 0.03.