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. 2020 Jan 10;10:115. doi: 10.1038/s41598-019-56809-w

Table 5.

Pearson correlation coefficients between the relative concentration of 34 identified plasma metabolites and Bovine Respiratory Disease defined through six reference diagnosis methods.

Metabolite Visual Temperature Lung Auscultation Clinical Diagnosis Visual-Clinical Lung Lesions
1-methyl-histidine −0.42+ −0.28+ −0.28+ −0.35+ −0.39+ −0.20***
3-hydroxyisobutyrate 0.45+ 0.18** 0.19*** 0.25+ 0.44+ 0.20***
Acetate −0.28+ −0.28+ −0.23+ −0.25+ −0.26+ −0.06
Acetone 0.42+ 0.10 0.21*** 0.27+ 0.41+ 0.18**
Alanine −0.43+ −0.23+ −0.22+ −0.30+ −0.41+ −0.25+
Choline −0.01 0.02 −0.02 0.01 0.01 −0.13*
Citrate −0.63+ −0.35+ −0.33+ −0.38+ −0.61+ −0.36+
Creatine 0.11 0.17** 0.11 0.12* 0.14* −0.12*
Creatinine 0.49+ 0.31+ 0.23+ 0.31+ 0.48+ 0.24+
Dimethyl sulfone 0.03 −0.02 −0.03 0.07 0.03 −0.05
Ethanol 0.23+ 0.06 0.01 0.04 0.23+ 0.12*
Formate 0.04 −0.05 −0.02 0.03 0.06 −0.02
Glucose −0.41+ −0.32+ −0.19*** −0.29+ −0.40+ −0.09
Glutamate −0.59+ −0.46+ −0.42+ −0.48+ −0.57+ −0.27+
Glutamine −0.63+ −0.48+ −0.43+ −0.51+ −0.61+ −0.29+
Glycine −0.29+ −0.28+ −0.24+ −0.25+ −0.28+ −0.10
Glycoprotein acetyls −0.29+ −0.16** −0.22+ −0.20*** −0.28+ −0.12*
Hydroxybutyrate 0.64+ 0.35+ 0.39+ 0.44+ 0.64+ 0.33+
Hydroxyisobutyrate −0.33+ −0.29+ −0.22*** −0.27+ −0.31+ −0.14*
Isobutyrate 0.15* −0.01 −0.04 −0.02 0.15** 0.07
Isoleucine 0.49+ 0.24+ 0.23+ 0.27+ 0.47+ 0.27+
Isopropanol 0.21*** 0.05 0.01 0.04 0.21*** 0.10
Lactate 0.09 0.16** 0.16** 0.16** 0.08 0.01
Leucine 0.47+ 0.25+ 0.23+ 0.26+ 0.48+ 0.23***
Low Density Lipid −0.42+ −0.22*** −0.27+ −0.31+ −0.42+ −0.24+
Mannose 0.48+ 0.36+ 0.34+ 0.31+ 0.48+ 0.24+
Methanol 0.05 −0.12* −0.09 −0.08 0.06 0.03
Phenylalanine 0.49+ 0.46+ 0.20*** 0.30+ 0.50+ 0.24+
Pyruvate 0.44+ 0.45+ 0.32+ 0.34+ 0.42+ 0.12*
Succinate 0.09 −0.06 −0.02 0.02 0.10 0.14*
Tyrosine −0.67+ −0.49+ −0.39+ −0.48+ −0.65+ −0.27+
Unsaturated lipid −0.38+ −0.19*** −0.25+ −0.30+ −0.38+ −0.23+
Valine −0.48+ −0.36+ −0.30+ −0.34+ −0.46+ −0.26+
α glucose chain 0.66+ 0.49+ 0.35+ 0.38+ 0.64+ 0.32+