Table 1.
15 MRI studies included in region-of-interest meta-analysis comparing participants with PTSD to participants without PTSD.
Study | Participants with PTSD (N) | Comparison Participants without PTSD (N) | Comparison Participants without Trauma Exposure (N) | Comparison Participants with Trauma Exposure (N) | Diagnosti c Criteria | Average Agea | Method for ROI segmentation |
---|---|---|---|---|---|---|---|
Ahmed et al. (15) | 21 | 32 | - | 32 | DSM-IV | 15.3 | Automatedc |
Carrion et al. (9)b | 24 | 24 | 24 | - | DSM-IV | 11.0 | Manual |
Carrion et al. (68)b | 24 | 24 | 24 | - | DSM-IV | 11.0 | Manual |
De Bellis et al. (10)b | 44 | 61 | 61 | - | DSM-III-R | 12.1 | Manual |
De Bellis et al. (20) | 9 | 9 | 9 | - | DSM-IV | 10.5 | Manual |
De Bellis et al. (11)b | 28 | 66 | 66 | - | DSM-IV | 11.5 | Manual |
De Bellis et al. (70)b | 43 | 61 | 61 | - | DSM-IV | 12.1 | Manual |
De Bellis et al. (12)b | 61 | 122 | 122 | - | DSM-IV | 11.7 | Manual |
De Bellis et al. (71)b | 58 | 98 | 98 | - | DSM-IV | 12.0 | Manual |
De Bellis et al. (14) | 38 | 59 | 59 | 35 | DSM-IV | 10.5 | Manual Automatedc + |
Morey et al. (16) | 31 | 57 | 57 | 32 | DSM-IV | 10.4 | Manual |
Mutluer et al. (74) | 23 | 21 | 21 | - | DSM-IV | 15.4 | Manual |
Postel et al. (75) | 15 | 24 | 24 | - | DSM-IV | 16.0 | Manual |
Weems et al. (79)b | 24 | 24 | 24 | - | DSM-IV | 11.0 | Manual |
Weems et al. (42)b | 28 | 26 | 26 | - | DSM-IV | 13.8 | Automatedc |
Average age of all participants in sample (PTSD and comparison groups). None of the comparison participants listed above had a PTSD diagnosis at the time of the study
Despite overlapping samples present in overall database, none of the studies included in the individual ROI meta-analyses reported here contained overlapping samples
Automated method used was FreeSurfer image analysis suite.
“-” = not stated in the study.