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Survival following lethal MPXV challenge.
| Study ID | Study Group Assignment | MPXV Target Challenge Dose (PFU, IV) | Survival |
|---|---|---|---|
| Study 1 | Controls | 5.0E + 07 | 0/3 |
| ACAM2000 + Placebo | 5.0E + 07 | 6/6 | |
| ACAM2000 + Tecovirimat | 5.0E + 07 | 7/7 | |
| Study 2 | ACAM2000 + Placebo | 5.0E + 07 | 3/3 |
| ACAM2000 + Tecovirimat | 5.0E + 07 | 2/3 | |
| Study 3 | ACAM2000 + Placebo | 5.0E + 07 | 3/3 |
| ACAM2000 + Tecovirimat | 5.0E + 07 | 3/3 | |
