Table 3.
Association Between Individual Symptom Severity and Presence of Fatigue among Emerging Adults with Inflammatory Bowel Disease
| Unadjusted | Adjusteda | |||
|---|---|---|---|---|
| OR | P | OR | P | |
| Abdominal cramps | 1.49 [1.13, 1.95] |
0.01 | 1.48 [1.09, 2.0] |
0.01 |
| Abdominal pain | 1.5 [1.16, 2.14] |
0.01 | 1.53 [1.11, 2.11] |
0.01 |
| Diarrhea | 1.44 [1.09, 1.89] |
0.01 | 1.41 [1.05, 1.91] |
0.02 |
| Passing gas | 1.32 [1.05, 1.65] |
0.02 | 1.30 [1.02, 1.68] |
0.03 |
| Abdominal Tenderness | 1.49 [1.08, 2.05] |
0.02 | 1.43 [1.01, 2.02] |
0.04 |
| Bloating | 1.39 [1.04, 1.86] |
0.03 | 1.38 [1.0, 1.92] |
0.05 |
| Reduced appetite | 1.51 [0.97, 2.33] |
0.07 | 1.64 [0.99, 2.72] |
0.06 |
| Blood in stool | 1.28 [0.87, 1.87] |
0.21 | 1.27 [0.83, 1.94] |
0.28 |
| Nausea or vomiting | 1.18 [0.92, 1.51] |
0.20 | 1.20 [0.90, 1.59] |
0.21 |
| Weight loss | 1.09 [0.52, 2.27] |
0.83 | 1.21 [0.56, 2.62] |
0.63 |
| Constipation | 1.02 [0.8, 1.3] |
0.86 | 0.96 [0.73, 1.26] |
0.77 |
| Increased appetite | 1.01 [0.71, 1.43] |
0.95 | 0.98 [0.67, 1.44] |
0.93 |
OR = Odds Ratio
a
Adjusted for age, emerging adulthood IDEA-8 score, the interaction between age and emerging adulthood IDEA-8 score, gender, disease type, and current steroid use.
Note: The interaction between age and emerging adulthood IDEA-8 score was included since the effect of age may differ based on developmental stage. All participants reporting weight gain (n = 3) and fever (n = 3) also reported the presence of fatigue.