A: Core needle biopsy with flat epithelial atypia (FEA) and associated calcifications (H&E, 40X); inset: higher power showing duct involved by FEA (H&E, 200X); B: Tissue slice from excision specimen with biopsy site changes (upper right) and residual FEA (lower center) (H&E, 20X); C: Tissue slice from excision specimen with no biopsy site changes and focus of invasive carcinoma, 2.2 mm (H&E, 20X); D: Higher power of focus of invasive ductal carcinoma with lobular growth pattern and focal DCIS (H&E, 100X)