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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Am J Surg Pathol. 2020 Feb;44(2):182–190. doi: 10.1097/PAS.0000000000001385

Figure 4: Examples of cases reclassified following morphologic review.

Figure 4:

A: Flat proliferation with marked nuclear atypia – flat lesion shows prominent nucleoli, irregular nuclear outlines and increased nuclear to cytoplasmic ratio (H&E, 400X); B: Benign without atypia – columnar cell changes with prominent myoepithelial cell layer (H&E, 200X); C, D: Focal atypical ductal hyperplasia (ADH) – demonstrating a spectrum of architectural complexity ranging from minimal (C, H&E, 200X) to more developed ADH (D, H&E, 400X)