Table 1.
Baseline characteristics of Sister Study participants by colorectal case status (N=48,704)
| Colorectal cancer (case) |
Non-colorectal cancer (non-case) |
|||
|---|---|---|---|---|
| Participant Characteristic | 216 | 100% | 48,488 | 100% |
| Age at baseline, years (mean, range) | 216 | 59.9 (36.6-75.9) | 48,488 | 55.7 (35.0-76.5) |
| Follow up time, years (mean, range) | 216 | 5.0 (0.01-11.8) | 48,488 | 8.7 (0.1-12.7) |
| Diagnosis Source | ||||
| Medical report or NDI | 136 | 63.0 | -- | --- |
| Self-report/Next-of-kin | 80 | 37.0 | -- | --- |
| Missing | 0 | |||
| Race/ethnicity | ||||
| Non-Hispanic white | 183 | 84.7 | 41,064 | 84.7 |
| Non-Hispanic black | 18 | 8.3 | 3,901 | 8.1 |
| Hispanic/other | 15 | 6.9 | 3,513 | 7.3 |
| Missing | 0 | 10 | ||
| Educational attainment | ||||
| High school or less | 22 | 10.2 | 7,391 | 15.3 |
| Some college | 83 | 38.4 | 16,274 | 33.6 |
| Bachelor’s degree or above | 111 | 51.4 | 24,815 | 51.2 |
| Missing | 0 | 8 | ||
| Body mass index (kg/m2) (mean, range) | 216 | 28.9 (18.0-56.8) | 48,476 | 27.7 (11.5-72.1) |
| Smoking status | ||||
| Never | 111 | 51.4 | 27,229 | 56.2 |
| Former | 85 | 39.4 | 17,351 | 35.8 |
| Current | 20 | 9.3 | 3,896 | 8.0 |
| Missing | 0 | 12 | ||
| Alcohol status | ||||
| Nondrinker (never/former) | 46 | 21.3 | 9,109 | 18.8 |
| Light (<= 3 drinks per week) | 107 | 49.5 | 26,348 | 54.4 |
| Moderate (>3 - 7 drinks per week) | 36 | 16.7 | 7,568 | 15.6 |
| Heavy (> 7 drinks per week) | 27 | 12.5 | 5,385 | 11.1 |
| Missing | 0 | 78 | ||
| Menopausal status | ||||
| Premenopausal | 34 | 15.7 | 16,650 | 34.4 |
| Postmenopausal | 182 | 84.3 | 31,808 | 65.6 |
| Missing | 0 | 30 | ||
| Family history of colorectal cancer | 27 | 12.7 | 4,627 | 9.7 |
| Missing | 3 | 560 | ||
| Ever had colonoscopy | 139 | 64.4 | 30,159 | 62.2 |
| Missing | 0 | 16 | ||
| NSAID use in the past 12 months | 33 | 15.3 | 9,179 | 18.3 |
| Missing | 0 | 0 | ||
| Ever used HRT | 109 | 50.7 | 21,980 | 45.5 |
| Missing | 1 | 151 | ||
| Mean (Range) | Mean (Range) | |||
| Physical activity (total MET-hours per week) | 213 | 46.0 (7.2-157.8) | 48,078 | 50.8 (7.2-350.3) |
| Total caloric intake (kcal/day) | 216 | 1654.6 (429.8-3768.6) | 48,488 | 1616.9 (400.2-3997) |
| Unprocessed red meat intake (g/day) | 216 | 31.2 (0-239.1) | 48,488 | 28.4 (0-515.9) |
| Processed meat intake (g/day) | 216 | 16.7 (0.4-60.6) | 48,488 | 14.9 (0-165.6) |
| White meat intake (g/day) | 216 | 44.5 (0-199.8) | 48,488 | 42.6 (0-502.1) |
| Fruit and vegetable intake (cup eq) | 216 | 3.5 (0.5-11.7) | 48,488 | 3.4 (0-21.0) |
| Dairy intake (cup eq) | 216 | 1.4 (0.1-5.5) | 48,488 | 1.4 (0.02-9.4) |
| Fiber intake (g/day) | 216 | 16.8 (4.6-44.3) | 48,488 | 17.0 (0-82.4) |
| Fat intake (g/day) | 216 | 69.8 (16.7-198.8) | 48,488 | 67.8 (4.0-268.1) |
| Dietary and supplementary folate (DFE) | 216 | 927.6 (140.5-2579.6) | 48,488 | 939.6 (22.1-3865.1) |
| Dietary and supplementary calcium (mg/d) | 216 | 1261.4 (205.2-3132.7) | 48,488 | 1292.2 (63.0-5738.8) |
NOTE: NDI = National Death Index; NSAID = nonsteroidal anti-inflammatory drugs; HRT = hormone replacement therapy; MET = metabolic equivalent of task; DFE = dietary folate equivalents.