| 1. |
Inhibition of brain hemichannels by transactivator of transcription-linked Gap19 (TAT-Gap19) |
Impairment in the spatial memory in Y maze task |
[14] |
| 2. |
Microinfusion of TAT-Cx43L2 and Gap27, inhibitors of connexin 43 hemichannels, into the basolateral amygdala |
Development of amnesia during fear conditioning |
[16] |
| 3. |
d-Galactose-induced AD in ovariectomy-subjected mice |
Disruptions in the structural integrity of neuronal-glial units and decreased expressions of connexin 43 |
[19] |
| 4. |
Depletion of drebrin, a binding partner of the connexin 43, using siRNA |
Cognitive decline along with a decrease in connexin 43 |
[20–23] |
| 5. |
Comparison of slices of the hippocampal CA1 area obtained from connexin 36 knockout and normal mice |
Significant reduction in LTP in the hippocampal slices obtained from connexin 36 knockout mice |
[26] |
| 6. |
Evaluation of memory in connexin 36 knockout mice |
Impairment in spatial short-term memory in these mice |
[27] |
| 7. |
Evaluation of changes in connexin levels during memory consolidation in the passive avoidance test |
Up-regulation of connexins 36 and 45 mRNAs in the hippocampus |
[28] |
| 8. |
Chronic cerebral hypoperfusion by permanent occlusion of carotid arteries-induced vascular dementia |
The decrease in the mRNA and protein expression of connexins 32 and 36 in the hippocampus |
[30] |
