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Summary of comparison results for the four DMR identification methods
| Small effect size | Large effect size | |||||
|---|---|---|---|---|---|---|
| Method | Precision | Power | Precision | Power | Speed | Can model covariate variable |
| bumphunter | - | - | + | - | + | Yes |
| combp | ++ | - | ++ | ++ | + | Yes |
| DMRcate | ++ | -- | ++ | + | ++ | Yes |
| Probe Lasso | + | -- | ++ | + | ++ | No |
A ‘--’ and ‘-’ indicate very unsatisfactory and unsatisfactory results for the given criterion, respectively. A ‘+’ and ‘++’ indicate good and very good results for the given criterion, respectively.
