Table 3.

Off-target score of ASO2-cEt/DNA delivered in vitro and in vivo

	% PKM1	AK2	PROM1	RER1	CLIP4	UCK2	PTOV1
Transfection in vitro	34.0 (2.9)	0.3 (0.06)	0.0 (0.0)	1.1 (0.20)	0.3 (0.06)	0.9 (0.09)	0.0 (0.01)
Free uptake in vitro	18.0 (1.8)	0.0	0.0	0.1 (0.01)	0.0	0.1 (0.0)	0.0
s.c. delivery in vivo*	11.7 (1.3)	0.0	not expr.	0.3 (0.07)	0.0	0.0	0.0

Data represent mean (SE) relative to PKM; s.c. subcutaneous; *GN3-conjugated ASO2-cEt/DNA.