Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Nov 28;48(2):924–933. doi: 10.1093/nar/gkz1096

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 5. — Influence of labeling on dsRNA structure. (A) Average structures of the labeled and unlabeled dsRNA simulations. The position of the molecules and abasic sites are depicted in red at the unlabeled structure. (B) Atom position root mean square fluctuations of -labeled dsRNA, color coded on a representative MD structure. The averaged structure of the labeled dsRNA simulation was taken as the reference state. regions are highlighted with black ellipses. (C) interactions in a dsRNA. Stable hydrogen bonds between and the complementary cytidine are shown as dashed lines. An additional hydrogen bond formed between (N9) and the abasic site (O4′).

Inline graphic — Influence of labeling on dsRNA structure. (A) Average structures of the labeled and unlabeled dsRNA simulations. The position of the molecules and abasic sites are depicted in red at the unlabeled structure. (B) Atom position root mean square fluctuations of -labeled dsRNA, color coded on a representative MD structure. The averaged structure of the labeled dsRNA simulation was taken as the reference state. regions are highlighted with black ellipses. (C) interactions in a dsRNA. Stable hydrogen bonds between and the complementary cytidine are shown as dashed lines. An additional hydrogen bond formed between (N9) and the abasic site (O4′).