Table 1.

Comparison of structural and biophysical parameters in MITF(wt) and MITF(Δ)

	MITF(wt)	MITF(Δ)
PDB	4ATH	6FX5
Resolution [Å]	1.95	2.05
Sequence segments	A: 216–295, B: 214–295	A: 220–295, B: 217–293
Coiled coil interface [Å2]	1,125	1,094
Accommodation index	−0.5	0.0
Maximum asymmetry index (residue) [Å]	0.56 (261)	0.21 (269)
Thermal unfolding midpoint [°C]	42.7	60.9
Permissive dimerization partners	MITF(wt), TFEB	MITF(Δ), MAX