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. 2019 Nov 28;48(2):934–948. doi: 10.1093/nar/gkz1104

Table 3.

Binding of MITF to DNA recognition elements

MITF (Δ) MITF (wt)
M-box K D [nM] 1.3 ± 0.3 × 101 2.5 ± 0.5
Binding stoichiometry (n) 0.499 ± 0.008 0.505 ± 0.010
E-box K D [nM] 1.0 ± 0.1 × 101 1.7 ± 0.2
Binding stoichiometry (n) 0.503 ± 0.006 0.492 ± 0.018
Synthetic random K D [nM] 3.0 ± 0.6 × 102 4.9 ±0.4 × 102
Binding stoichiometry (n) 0.464 ± 0.016 0.505 ± 0.04
Selectivity M-box / Synthetic random 23 196
E-box / Synthetic random 30 288