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PET imaging studies of tumor-bearing models (n = 3). (A) Dynamic PET scanning of A375-hPD-L1 (with or without injection of KN035) and MCF-7 tumor–bearing models over 0–2 h after injection of 4.0–5.0 MBq of 68Ga-NOTA-Nb109. (B and C) Biodistribution of 68Ga-NOTA-Nb109 and tumor-to-muscle (T/M) ratio analyzed according to quantification analysis of PET images.
