Table 2.
History regarding heat intolerance prior to enrolment
| Code | Unexplained fevers | Associated seizures | Hospitalization due to heat intolerance | If yes, diagnosis | Reported heat intolerance | Impact of heat intolerance/reduced sweating on: | |||
|---|---|---|---|---|---|---|---|---|---|
| daily life | outdoor sports | choice of vacation destinations | ability to travel | ||||||
| Male subjects | |||||||||
| M3–001 | Y | N | N | / | Y | N | N | Y | Y |
| M3–002 | Y | N | Y | suspicion of pneumonia | Y | Y | N | Y | Y |
| M3–003 | Y | N | N | / | Y | Y | N | Y | Y |
| M3–005 | Y | N | Y | therapy-resistant hyperpyrexia | Y | Y | Y | Y | Y |
| M3–007 | Y | N | N | / | Y | N | N | Y | Y |
| M3–008 | Y | Y | Y | spasmodic laryngitis | Y | N | N | Y | Y |
| M3–009 | Y | N | N | / | Y | N | N | Y | Y |
| M3–012 | Y | N | Y | suspicion of respiratory tract infection | Y | N | N | Y | Y |
| M3–013 | Y | N | N | / | Y | Y | N | Y | Y |
| M3–014 | Y | N | N | / | Y | N | N | Y | Y |
| M3–015 | Y | N | Y | hyperpyrexia | Y | Y | N | Y | Y |
| M3–016 | N | N | N | / | Y | N | N | Y | Y |
| M3–017 | Y | N | N | / | Y | Y | N | Y | Y |
| M3–018 | Y | N | Y | fever, dehydration | Y | Y | Y | Y | Y |
| M3–019 | Y | N | N | / | Y | N | Y | Y | Y |
| M3–020 | Y | N | N | / | Y | Y | Y | Y | Y |
| M3–022 | Y | N | N | / | Y | N | N | Y | Y |
| M3–023 | Y | N | N | / | Y | N | N | Y | Y |
| M3–025 | Y | N | Y | unexplained fever | Y | Y | Y | Y | Y |
| Female subjects | |||||||||
| F3–004 | N | N | N | / | N | N | N | N | N |
| F3–006 | N | N | N | / | N | N | N | N | N |
| F3–010 | N | N | N | / | N | N | N | N | N |
| F3–011 | N | N | N | / | N | N | N | N | N |
| F3–021 | N | N | N | / | N | N | N | Y | N |
| F3–024 | N | N | N | / | N | N | N | N | N |
Abbreviations: Y yes; N no