Table 5.
Ophthalmic assessments
| Code | Corneal examination | Meibomian gland openingsa | BUT (s) | OSDI score | Schirmer’s test (mm) | |||
|---|---|---|---|---|---|---|---|---|
| Right eye | Left eye | Right eye | Left eye | Right eye | Left eye | |||
| Male subjects | ||||||||
| M3–001 | SPK (on both sides) | 1 | 2 | 3 | 3 | 11.1 | 12 | 10 |
| M3–002 | N | 0 | 0 | 3 | 2 | 0.0 | 5 | 6 |
| M3–003 | SPK (on both sides) | 2 | 3 | 2 | 4 | 8.3 | u.a. | u.a. |
| M3–005 | N | 3 | 1 | 5 | 4 | 5.0 | 11 | 5 |
| M3–007 | N | 0 | 0 | 10 | 12 | 2.5 | u.a. | u.a. |
| M3–008 | SPK (on both sides) | 2 | 3 | 1 | 2 | 13.8 | 20 | u.a. |
| M3–009 | N | 5 | 4 | 4 | 4 | 5.0 | 10 | 4 |
| M3–012 | N | 0 | 0 | u.a. | u.a. | 5.0 | 12 | 17 |
| M3–013 | SPK (on both sides) | 1 | 3 | 5 | 5 | 11.1 | 6 | 11 |
| M3–014 | N | 1 | 1 | 10 | 11 | 5.0 | 7 | 4 |
| M3–015 | u.a. | 0 | 3 | 5 | 6 | 8.3 | u.a. | u.a. |
| M3–016 | SPK (on both sides) | 0 | 0 | 8 | 10 | 5.5 | u.a. | u.a. |
| M3–017 | N | 0 | 2 | 12 | 12 | 2.7 | 14 | > 25 |
| M3–018 | SPK (on both sides) | 1 | 2 | 4 | 4 | 19.4 | u.a. | u.a. |
| M3–019 | N | 6b | 9b | 7 | u.a. | 2.7 | 16 | 10 |
| M3–020 | SPK (on both sides) | 1 | 0 | u.a. | u.a. | 22.2 | u.a. | u.a. |
| M3–022 | N | 1 | 1 | u.a. | u.a. | 5.0 | u.a. | u.a. |
| M3–023 | N | 1 | 0 | u.a. | u.a. | 5.0 | u.a. | u.a. |
| M3–025 | N | 6 | 6 | u.a. | u.a. | 2.7 | > 25 | > 25 |
| Average | / | 1.39 | 1.72 | 5.64 | 6.08 | 7.38 | / | / |
| SD | / | 1.72 | 1.71 | 3.30 | 3.77 | 5.85 | / | / |
| Female subjects | ||||||||
| F3–004 | N | > 20 | > 20 | 14 | 14 | 0.0 | u.a. | u.a. |
| F3–006 | N | 9 | 8 | 14 | 12 | 11.1 | u.a. | u.a. |
| F3–010 | N | 8 | 5 | 8 | 6 | 2.5 | 4 | u.a. |
| F3–011 | N | > 20 | > 20 | 9 | 8 | 2.5 | 10 | 5 |
| F3–021 | N | 6 | 5 | 12 | 10 | 0.0 | > 25 | > 25 |
| F3–024 | N | 5 | 5 | u.a. | u.a. | 0.0 | u.a. | u.a. |
Abbreviations: a, maximum number detected in the lower lid during two independent examinations; N, normal; SPK, superficial punctate keratitis; u.a., unable to assess; b, not fully developed