Recruitment characteristics |
Number of patients screened for trial participation |
Used to generate randomisation rate outcome |
Number of patients randomised into the trial |
Used to generate randomisation rate, recruitment rate and dropout outcomes |
Number of patients who drop out |
Used to generate dropout outcome |
Number of sites used for recruitment |
Used to generate recruitment rate outcome |
Continent of recruitment |
Recruitment has been shown to differ between countries [1, 2] |
Recruitment strategy |
The recruitment strategies/methods adopted by trials may affect recruitment efficiency [3] |
Profession of the recruiter |
The profession of the recruiter may play a role in willingness of patients to take part in trials [2, 4]. Some professions have been described as ‘gatekeeping’ during the recruitment process [5] |
Number of recruiters per site |
The number of people responsible for recruitment may reduce recruitment efficiency [6–9] |
Trial characteristics |
Publication date |
There is evidence to suggest recruitment of stroke survivors for clinical trials is becoming less efficient [10, 11] |
Type of intervention |
The treatments on offer can be a motivating factor for potential participants [12, 13] |
Targeted impairment |
Control condition |
Stroke survivor residence |
Recruitment from a community setting may lead to more efficient recruitment to RCTs [11]. Recruitment of acute stroke survivors within a hospital setting has been highlighted as a problematic recruitment area [10, 11] |
Stage of rehabilitation |
Funding support |
There are potential issues of bias when certain funding bodies are used [14]. Trialists may be influenced by institution pressures to secure funding [15] |
Ethics approval |
Trialists are concerned by the impact of research governance on the recruitment process [15, 16] |