Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jan 10;21:14. doi: 10.1186/s12931-019-1257-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 5 — The potential mechanism of drugs in asthma. (a): The potential mechanism of Tretinoin (ATRA) in asthma. ATRA decreased Th2 cytokines by inhibiting GATA-3 and up-regulating T-bet expression, also, ATRA inhibited the expression of RORγt, thus decreased the level of IL-17A and the downstream proinflammatory factors. (b): The potential mechanism of Quercetin in asthma. Quercetin inhibited gene expression of pro-inflammatory cytokine (TNF-a, IL-1b, IL-6, and IL-8) by regulating the activation of NF-κB and p38 MAPK