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. 2020 Jan 10;21:13. doi: 10.1186/s12931-019-1254-0

Table 2.

Incidence of Postoperative Pulmonary Complications (PPCs) by DLco Status

PPC Type of the PPC Mortality
ARDS/Pneumonia Respiratory failure Air leakage BPF/empyema Atelectasis 30-day 90-day
Overall 79 (24.6) 49 (15.3) 23 (7.2) 19 (5.9) 14 (4.4) 10 (3.1) 2 (0.6) 26 (8.1)
DLco at diagnosis
 Normal (N = 165) 24 (14.5) 14 (8.5) 4 (2.4) 5 (3.0) 4 (2.4) 4 (2.4) 0 (0) 5 (3.0)
 Low (N = 156) 55 (35.3) 35 (22.4) 19 (12.2) 14 (9.0) 10 (6.4) 6 (3.9) 2 (1.3) 21 (13.5)
P value <.001 .001 <.001 .024 .081 .533a .234a .001
Change before and after CCRT
 NN: Normal → Normal (N = 76) 7 (9.2) 3 (4.0) 0 (0) 1 (1.3) 2 (2.6) 1 (1.3) 0 (0) 1 (1.3)
 NL: Normal → Low (N = 89) 17 (19.1) 11 (12.4) 4 (4.5) 4 (4.5) 2 (2.3) 3 (3.4) 0 (0) 4 (4.5)
 LL: Low → Low (N = 75) 23 (31.7) 14 (18.7) 7 (9.3) 7 (9.3) 5 (6.7) 2 (2.7) 1 (1.3) 10 (13.3)
 LVL: Low → Very Low (N = 81) 32 (39.5) 21 (25.9) 12 (14.8) 7 (8.6) 5 (6.2) 4 (4.9) 1 (1.2) 11 (13.6)
P for trends <.001 <.001 <.001 .030 .148 .255 .260 .002

ARDS acute respiratory distress syndrome; BPF bronchopleural fistula; DLco diffusing capacity of the lung for carbon monoxide; PPC postoperative pulmonary complication;

a Fisher’s exact test