Table 3.
Multivariable analysis for having ARDS associated with non-pulmonary sepsis (n = 594)
| Variable | Odds ratio (95% CI) | P value | |
|---|---|---|---|
| Age at admission—per year | 0.99 (0.97–1.01) | 0.29 | |
| Male gender | 1.33 (0.71–2.49) | 0.37 | |
| Admission source | Hospital wards and other hospitals | Reference | |
| Emergency department | 1.89 (1.06–3.40) | 0.03 | |
| Intensive care unit | 0.96 (0.25–3.65) | 0.95 | |
| Body mass index—kg/m2 | 1.04 (0.98–1.09) | 0.19 | |
| Smoking | Never | Reference | |
| Former | 0.77 (0.39–1.54) | 0.46 | |
| Current | 0.18 (0.06–0.59) | 0.004 | |
| Coexisting conditions | Congestive heart failure | 0.72 (0.26–1.88) | 0.50 |
| COPD | 1.54 (0.46–5.21) | 0.49 | |
| Diabetes mellitus | 0.69 (0.35–1.37) | 0.29 | |
| Regular medication | Glucocorticoids | 0.48 (0.19–1.22) | 0.12 |
| Statin | 0.36 (0.10–1.24) | 0.11 | |
| Site of infection | Abdomen | Reference | |
| Urinary tract | 0.71 (0.33–1.55) | 0.39 | |
| Soft tissue | 2.37 (1.04–5.40) | 0.04 | |
| Other than abdomen, urinary tract, or soft tissue | 1.57 (0.74–3.32) | 0.24 | |
| Septic shock | 1.43 (0.74–2.78) | 0.29 | |
| APACHE II score—per point | 1.08 (1.05–1.12) | < 0.001 |
ARDS acute respiratory distress syndrome, CI confidence interval, COPD chronic obstructive pulmonary disease, APACHE II acute physiology and chronic health evaluation II
Definition of categorical variables: other than abdomen, urinary tract, or soft tissue = central nervous system, intravenous catheter, osteoarticular, endocardium, wound, implant device, and others
Missing data (due to missing data of each outcome measures): admission source = 1; body mass index = 9; smoking = 45; APACHE II score = 53