Table 2.
Bronchoalveolar lavage fluid cell counts in Sprague Dawley rats
| Total cell number (106) | Macrophages (106) | Neutrophils (106) | |
|---|---|---|---|
| Week 12 – exposure | |||
| Air + Reg | 3.83 + 0.4 | 3.83 + 0.4 | 0.00 + 0.0 |
| Air + HF | 4.46 + 0.5 | 4.46 + 0.5 | 0.00 + 0.0 |
| GMA-SS + Reg | 92.1 + 13.0 ab | 77.6 + 11.0 ab | 14.5 + 5.2 abc |
| GMA-SS + HF | 68.0 + 9.7 ab | 65.3 + 9.7 ab | 2.71 + 1.3 ab |
| Week 24 – recovery | |||
| Air + Reg | 4.66 + 0.5 | 4.65 + 0.5 | 0.01 + 0.01 |
| Air + HF | 3.51 + 0.4 | 3.50 + 0.4 | 0.01 + 0.01 |
| GMA-SS + Reg | 6.94 + 1.1b | 4.99 + 0.5 | 0.16 + 0.01 |
| GMA-SS + HF | 4.92 + 0.8 | 4.87 + 0.7 | 0.06 + 0.02 |
Total cell number, macrophages and neutrophils in the bronchoalveolar lavage fluid from Sprague Dawley rat lungs at week 12 after a 5-week exposure to 20 mg/m3 of GMA-SS; and at week 24 after a 12 week recovery period. Mean ± SD (n = 6). Significant effects are highlighted in bold
aSignificantly different from Air+Reg diet (p < 0.05)
bSignificantly different from Air+HF diet (p < 0.05)
cSignificantly different from GMA-SS + HF diet (p < 0.05)