Table 3.
Bronchoalveolar lavage fluid cell counts in Brown Norway rats
| Total cell number (106) | Macrophages (106) | Neutrophils (106) | |
|---|---|---|---|
| Week 12 – exposure | |||
| Air + Reg | 12.8 + 1.2 | 12.7 + 1.1 | 0.14 + 0.1 |
| Air + HF | 8.7 + 0.2 | 8.7 + 0.2 | 0.00 + 0.0 |
| GMA-SS + Reg | 62.1 + 4.4 ab | 52.4 + 4.2 ab | 9.66 + 2.6 ab |
| GMA-SS + HF | 76.5 + 4.7 ab | 68.9 + 3.7 ab | 7.39 + 1.3 ab |
| Week 24 – recovery | |||
| Air + Reg | 18.0 + 2.3 | 18.0 + 2.3 | 0.04 + 0.04 |
| Air + HF | 14.4 + 3.3 | 14.4 + 3.3 | 0.00 + 0.0 |
| GMA-SS + Reg | 43.2 + 3.1 ab | 28.4 + 2.5 ab | 14.9 + 2.1 ab |
| GMA-SS + HF | 49.9 + 6.6 ab | 35.7 + 4.1 ab | 14.2 + 2.8 ab |
Total cells number, macrophages and neutrophils in the bronchoalveolar lavage fluid from Brown Norway rat lungs at week 12 after a 5-week exposure to 20 mg/m3 of GMA-SS, and at week 24 after a 12 week recovery period. Mean ± SD (n = 6). Significant effects are highlighted in bold
aSignificantly different from Air+Reg diet (p < 0.05)
bSignificantly different from Air+HF diet (p < 0.05)