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. 2020 Jan 7;13:131–142. doi: 10.2147/OTT.S217335

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© 2020 Wang et al.

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The overexpression of BAMBI attenuated the inhibitory effects on cell proliferation, migration, and invasion and the promotion effect on cell apoptosis mediated by PVT1 knockdown. (A–B) The protein level of BAMBI in A549 and H1299 cells transfected with NC, si-control or si-PVT1 were detected by Western blot. (C–H) The A549 and H1299 cells were transfected with si-control, si-PVT1, si-PVT1 + pcDNA-control or si-PVT1 + pcDNA-BAMBI. (C–D) The cell viability was examined via MTT assay. (E–F) The apoptotic rate was evaluated through flow cytometry. (G–H) The number of migration and invasion cells was measured via Transwell assay. *P < 0.05.