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. 2020 Jan 7;13:9–17. doi: 10.2147/DMSO.S225796

Table 2.

Principal Characteristics and Adverse Events or Complications in Relation to the Presence of Diabetes and Stress Hyperglycemia

Variable Diabetes, No SH (N=143) Diabetes, SH+ (N=53) No Diabetes, SH+ (N=6) P value^
DM (No SH vs. SH+)
P value^
SH+ vs No SH
Admission glucose (mg/dL) 140.6 ± 34.5 230.1 ± 68.0 159.8 ± 7.8 <0.001 <0.001
HbA1c (mmol/mol) 7.11 ± 1.01 7.09 ± 0.97 6.10 ± 0.38^ 0.887 0.425
Relative hyperglycemia 0.90 ± 0.17 1.47 ± 0.37 1.26 ± 0.13 <0.001 <0.001
Age (years) 73.5 ± 12.7 76.0 ± 11.6 83.3 ± 7.7 0.136 0.085
Age-adjCharlson Index 5.08 ± 2.17 5.55 ± 2.01 5.50 ± 1.76 0.171 0.156
Type of surgery (Major) 120 (83.9, 76.6–88.7) 47 (88.7, 76.3–94.1) 6 (100.0, 51.7–100.0) 0.500 0.378
Cases with events 33 (23.1, 16.6–30.3) 29 (54.7, 40.6–66.5) 5 (83.3, 36.6–94.0) <0.001 <0.001
Cardiovascular events 6 (4.2, 1.7–8.4) 10 (18.9, 9.9–30.3) 4 (66.7, 24.1–86.1 <0.001 <0.001
 AMI/angina 2 (1.4, 0.2–4.4) 2 (3.8, 0.7–11.4) 1 (16.7, 0.9–48.3) 0.296 0.150
 Stroke/TIA 0 (0.0–1.9) 1 (1.9, 0.1–8.4) 0 (0.0–27.3) 0.270 0.292
 Heart failure 1 (0.7, 0.0–3.3) 5 (9.4, 3.5–19.1) 1 (16.7, 0.9–48.3) 0.006 0.003
Arrhythmias 4 (2.5, 0.4–7.7) 5 (9.4, 3.5–19.1) 2 (33.3, 6.0–63.5) 0.062 0.016
Local infections 3 (2.1, 0.5–5.5) 2 (3.8, 0.7–11.4) 0 (0.0–27.3) 0.613 0.630
Systemic infections 21 (14.7, 9.5–21.0) 22 (41.5, 28.4–54.0) 3 (50.0, 13.9–75.9) <0.001 <0.001
Other complications 3 (2.1, 0.5–5.5) 6 (11.3, 4.7–21.4) 1 (16.7, 0.9–48.3) 0.013 0.007
ICU admission 6 (4.2, 1.7–8.4) 4 (7.5, 2.4–16.6) 1 (16.7, 0.9–48.3) 0.464 0.304
Reintervention 0 (0.0–1.9) 3 (5.7, 1.5–14.1) 1 (16.7, 0.9–48.3) 0.117 0.007

Notes: Data are presented as means ± SD or as number of cases (%, 95% confidence interval). ^Student t-test, Chi2 test or Fisher exact test, as appropriate).

Abbreviations: AMI, acute myocardial infarction; ICU, intensive care unit; TIA, transient ischemic attack; SH, stress hyperglycemia.