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. 2020 Jan 7;12:59–70. doi: 10.2147/CMAR.S228570

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© 2020 Xu et al.

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X-tile analysis of OS was performed using patients’ data to determine the optimal cut-off values for D-dimer, NLR, PLR, LMR, and CAR. The sample of spinal metastatic CCRCC patients was equally divided into training and validation sets. X-tile plots of training sets are shown in the left panels, with plots of matched validation sets shown in the small inset. The optimal cut-off values highlighted by the black circles in left panels are shown in histograms of the entire cohort (middle panels), and Kaplan-Meier plots are displayed in right panels. P values were determined by using the cut-off values defined in training sets and applying them to validation sets. The optimal cut-off values for NLR, PLR, LMR, and CAR were 3.8, 206.9, 2.3, and 1.2, respectively. (A) NLR, (B) PLR, (C) LMR, and (D) CAR.