Fig. 2.

Time to first relapse over 2 years in the PRISMS/SPECTRIMS with baseline disease activity^a subgroup. ^aActive disease defined as having either ≥ 1 relapse within 2 years before baseline or ≥ 1 gadolinium-enhancing lesion at baseline. Hazard ratio and p value based on Cox proportional hazards model, adjusted for number of relapses within 2 years prior, age group (<40 vs ≥ 40 years), and baseline burden of disease. CI confidence interval, EDSS Expanded Disability Status Scale, IFN β-1a interferon beta-1a, sc subcutaneous, tiw three times weekly