Table 3c.
Comparison of sensitivity and specificity estimates between PHQ-8 and PHQ-9 among studies that used the MINI reference standard
| PHQ-8a | PHQ-9 | PHQ-8 – PHQ-9 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cutoff | Sensitivity | 95% CI | Specificity | 95% CI | Sensitivity | 95% CI | Specificity | 95% CI | Sensitivity | 95% CI | Specificity | 95% CI |
| 5 | 0·96 | (0·93, 0·98) | 0·58 | (0·50, 0·65) | 0·97 | (0·93, 0·98) | 0·57 | (0·49, 0·65) | −0·01 | (−0·01, 0·00) | 0·01 | (0·00, 0·02) |
| 6 | 0·92 | (0·85, 0·96) | 0·67 | (0·59, 0·74) | 0·93 | (0·86, 0·97) | 0·66 | (0·59, 0·73) | −0·01 | (−0·03, 0·00) | 0·01 | (0·00, 0·02) |
| 7 | 0·89 | (0·81, 0·94) | 0·73 | (0·67, 0·79) | 0·89 | (0·81, 0·94) | 0·73 | (0·66, 0·79) | 0·00 | (−0·03, 0·00) | 0·01 | (0·00, 0·01) |
| 8 | 0·83 | (0·75, 0·89) | 0·80 | (0·75, 0·84) | 0·86 | (0·77, 0·91) | 0·79 | (0·74, 0·83) | −0·03 | (−0·06, 0·00) | 0·01 | (0·00, 0·02) |
| 9 | 0·78 | (0·69, 0·85) | 0·85 | (0·81, 0·89) | 0·81 | (0·71, 0·88) | 0·84 | (0·80, 0·88) | −0·03 | (−0·07, −0·00) | 0·01 | (0·00, 0·02) |
| 10 | 0·72 | (0·63, 0·79) | 0·88 | (0·84, 0·91) | 0·75 | (0·66, 0·82) | 0·88 | (0·84, 0·91) | −0·03 | (−0·08, −0·01) | 0·01 | (0·00, 0·02) |
| 11 | 0·65 | (0·57, 0·73) | 0·91 | (0·88, 0·94) | 0·69 | (0·61, 0·77) | 0·90 | (0·87, 0·93) | −0·04 | (−0·08, −0·01) | 0·01 | (0·00, 0·02) |
| 12 | 0·59 | (0·51, 0·66) | 0·93 | (0·91, 0·95) | 0·65 | (0·56, 0·73) | 0·92 | (0·90, 0·94) | −0·06 | (−0·11, −0·02) | 0·01 | (0·00, 0·02) |
| 13 | 0·53 | (0·44, 0·62) | 0·95 | (0·93, 0·97) | 0·57 | (0·49, 0·66) | 0·94 | (0·92, 0·96) | −0·04 | (−0·09, −0·01) | 0·01 | (0·00, 0·02) |
| 14 | 0·43 | (0·35, 0·51) | 0·97 | (0·95, 0·98) | 0·49 | (0·49, 0·49) | 0·96 | (0·96, 0·96) | −0·06 | (−0·11, −0·02) | 0·01 | (0·00, 0·02) |
| 15 | 0·37 | (0·29, 0·45) | 0·98 | (0·96, 0·99) | 0·42 | (0·42, 0·42) | 0·97 | (0·97, 0·97) | −0·05 | (−0·10, −0·02) | 0·01 | (0·00, 0·01) |
a
N Studies = 14; N Participants = 2,784; N major depression = 517
CI: confidence interval; MINI: Mini International Neuropsychiatric Interview