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IL-1 Signaling pathway and downstream effector molecules
IL-1R - interleukin-1 receptor; IL-1RAcP - IL-1 receptor accessory protein; TIR - Toll/interleukin-1 receptor kinase; MyD88 - myeloid differentiation factor 88; IRAK - IL-1R associated kinase; TRAF-6 - tumor necrosis factor receptor-associated factor-6; SERCA - sarcoplasmic/endoplasmic reticulum calcium ATPase; NOS - nitric oxide synthase; TNF-α - tumor necrosis factor-α
