Table 1.
Comparison of baseline clinical characteristics and laboratory parameters of the patients
| Variable | Atorvastatin | Rosuvastatin n=33 | P-value n=30 |
|---|---|---|---|
| Age, years | 57.67±9.35 | 58.30±11.98 | 0.815 |
| Male gender, n (%) | 29 (87.9) | 26 (86.7) | 0.885 |
| Body mass index (kg/m2) | 26.33±2.06 | 25.87±1.24 | 0.296 |
| Hypertension, n (%) | 9 (27.3) | 7 (23.3) | 0.720 |
| Diabetes mellitus, n (%) | 4 (12.1) | 7 (23.3) | 0.242 |
| Smoking, n (%) | 11 (33.3) | 8 (26.7) | 0.565 |
| STEMI, n (%) | 13 (39.4) | 16 (53.3) | 0.268 |
| LVEF, % | 48.9±9.5 | 44.4±9.0 | 0.060 |
| SBP, mm Hg | 119.70 ± 9.84 | 118.00±15.40 | 0.609 |
| DBP, mm Hg | 74.55±6.66 | 71.00±15.40 | 0.227 |
| Total cholesterol, mg/dL | 181.64±35.42 | 206.33±36.00 | 0.008 |
| LDL-C, mg/dL | 120.08±27.67 | 131.69±24.61 | 0.085 |
| HDL-C, mg/dL | 36.33±9.76 | 37.60±10.72 | 0.625 |
| Triglyceride, mg/dL* | 116.00 (87.00–182.00) | 154.50 (125.75–215.75) | 0.025 |
| TC/ HDL-C | 5.26±1.56 | 5.80±1.55 | 0.174 |
| Oxidized-LDL, ng/mL | 870.39±239.35 | 862.20±331.87 | 0.910 |
| ALT, IU/L | 27.21±14.51 | 27.30±14.14 | 0.981 |
| AST, IU/L | 33.85±15.80 | 30.57±13.84 | 0.386 |
| CK, IU/L | 118.97±23.82 | 114.77±28.47 | 0.526 |
| Endocan, pg/mL* | 110.27 (86.03–143.69) | 110.73 (77.28–165.22) | 0.934 |
| Chemerin, ng/mL* | 264.90 (196.00–525.95) | 309.95 (168.87–701.27) | 0.804 |
| Galectin-3, ng/mL* | 17.10 (13.10–22.25) | 18.25 (12.82–23.82) | 0.778 |
| Hb, g/dL | 14.41±1.60 | 14.21±1.45 | 0.620 |
| WBC, 103/µL | 10.24±2.62 | 10.59±3.09 | 0.634 |
| Platelet, 103/µL | 245.45±90.61 | 240.27±55.36 | 0.787 |
| Creatinine, mg/dL | 0.84 ±0.16 | 0.83±0.14 | 0.857 |
| BUN, mg/dL | 30.00±8.98 | 35.54±10.18 | 0.025 |
| Na+, mEq/L | 138.79±2.63 | 139.23±1.87 | 0.446 |
| K+, mEq/L | 4.23±0.40 | 4.19±0.39 | 0.660 |
| Coronary intervention | |||
| Drug eluting stent, n (%) | 13 (39.4) | 17 (56.7) | 0.095 |
| Bare metal stents, n (%) | 16 (48.5) | 13 (43.3) | |
| Medical therapy, n (%) | 4 (12.1) | 0 | |
| Number of revascularized vessels | |||
| 0, n (%) | 4 (12.1) | 0 (0) | 0.147 |
| 1, n (%) | 25 (75.8) | 25 (83.3) | |
| 2, n (%) | 3 (9.1) | 5 (16.7) | |
| 3, n (%) | 1 (0.5) | 0 (0) | |
Data given as mean±standard deviation or number (%)
*
Variables not showing normal distribution given as median (interquartile range)
ALT - alanine aminotransferase; AST - aspartate aminotransferase; BUN - blood urea nitrogen; CK - creatine kinase; DBP - diastolic blood pressure; HDL-C - high-density lipoprotein cholesterol; Hb - hemoglobin; LDL-C - low-density lipoprotein cholesterol; LVEF - left ventricular ejection fraction; TC - total cholesterol; Oxidized-LDL - oxidized low-density lipoprotein cholesterol; SBP - systolic blood pressure; STEMI - ST segment elevation myocardial infarction; WBC - white blood cells