Table 3.
Comparison of atorvastatin and rosuvastatin by means of absolute and percentage change of laboratory parameters
| Absolute change | Percent change, % | |||||
|---|---|---|---|---|---|---|
| Atorvastatin | Rosuvastatin | P-value | Atorvastatin | Rosuvastatin | P-value | |
| TC, mg/dL | -43±41 | -63±40 | 0.058 | -22±22 | -30±17 | 0.101 |
| LDL-C, mg/dL | -48±26 | -63±29 | 0.039 | -39±20 | -47±20 | 0.091 |
| HDL-C, mg/dL | 0.4±5.2 | 1.2±6.8 | 0.577 | 2.3±14.8 | 5.3±18.9 | 0.470 |
| TC/HDL-C | -1.37±1.21 | -1.99±1.27 | 0.054 | -23.1±18.6 | -32.6±16.5 | 0.038 |
| Triglyceride, mg/dL | 2 (-63.50–23.00) | -23.50 (-56.0 – -12.0) | 0.378 | 1.81 (-35.11–29.19) | -15.05 (-31.68–7.04) | 0.335 |
| Oxidized-LDL, ng/mL | -128±184 | -158±223 | 0.554 | -12.5±15.9 | -14.6±16.2 | 0.607 |
| Endocan, pg/mL | -9.73 (-55.84–18.91) | -28.91 (-57.18 – 12.63) | 0.349 | -7.96 (-43.75 – 27.64) | -26.61 (-46.56–15.65) | 0.349 |
| Chemerin, ng/mL | -134.10 (-323.90–-47.70) | -148.30 (-369.20–-34.40) | 0.815 | -42.79 (-64.72 – -26.68) | -56.08 (-72.06–-23.49) | 0.650 |
| Galectin-3, ng/mL | 0.10 (-4.80–4.25) | -2.25 (-7.97 – 1.25) | 0.141 | 0.88 (-19.96 – 28.57) | -16.23 (-30.70–9.13) | 0.071 |
| WBC, 103/µL | -2.1±2.6 | -2.9±2.6 | 0.255 | -17.3±22.2 | -23.2±19.9 | 0.275 |
HDL-C - high-density lipoprotein cholesterol; LDL-C - low-density lipoprotein cholesterol; Oxidized-LDL - oxidized low-density lipoprotein cholesterol; TC - total cholesterol;
WBC - white blood cells