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. Author manuscript; available in PMC: 2020 Jun 9.
Published in final edited form as: Nat Struct Mol Biol. 2019 Dec 9;27(1):8–13. doi: 10.1038/s41594-019-0345-4

Extended Data Fig. 4. Nucleosome-PWWP interface and comparison with other PWWP-DNA structures.

Extended Data Fig. 4

a. Nucleosome-PWWP interface. Residues colored in white recognize H3KC36me3 and residues colored in green interact with DNA.

b. Front and side view of DNA conformation comparison with other known PWWP-DNA structures. PDB code of the structures used are: 5XSK (HDGF) and 6IIS (HDGF3L, also known as HRP3).

c. Schematic view of DNA interactions. Electrostatic interactions and hydrogen bonds are shown as yellow dashes. SHLs are denoted.