Table 3.
Multivariate Analysis of Sex, Irritable Bowel Syndrome Types, Neurotrophic Factors, and Tight Junction Proteins With Abdominal Pain Severity
| Variable | Odds ratio (95% CI) | P-value |
|---|---|---|
| Female sex | 0.106 (0.006–1.866) | 0.125 |
| Age | 0.945 (0.872–1.024) | 0.170 |
| IBS-C | 1.000 (reference) | |
| IBS-D | 1.805 (0.095 – 34.350) | 0.695 |
| IBS-M | 33.193 (0.285–3872.180) | 0.149 |
| TRPV1 mRNA | 1.673 (0.291–9.622) | 0.564 |
| NGF mRNA | 1.490 (0.250–8.865) | 0.661 |
| GDNF mRNA | 0.495 (0.201–1.218) | 0.126 |
| ZO-1 mRNA | 0.407 (0.081–2.044) | 0.275 |
| Occludin mRNA | 0.167 (0.017–1.650) | 0.126 |
| Claudin-1 mRNA | 0.987 (0.424–2.294) | 0.975 |
IBS-C, constipation type irritable bowel syndrome; IBS-D, diarrhea type irritable bowel syndrome; IBS-M, mixed type irritable bowel syndrome; TRPV1, transient receptor potential vanilloid-1; NGF, nerve growth factor; GDNF, glial derived neurotrophic factor; ZO-1, zonula occludens-1.